Pascal Chappert

Affiliations

Inovarion, 75005, Paris, France.
Université de Paris, Institut Necker Enfants Malades, INSERM U1151, CNRS U8253, 75015, Paris, France.

Publications (18)

IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.

Nature communications

Avec: Irini Evnouchidou , Pascal Chappert , Samira Benadda , Andres Zucchetti , Mirjana Weimershaus , Marcelle Bens , Vivien Caillens , Despoina Koumantou , Sophie Lotersztajn , Peter van Endert , Jean Davoust , Pierre Guermonprez , Claire Hivroz , David A Gross , Loredana Saveanu

Prolonged response after TPO-RA discontinuation in primary ITP: results of a prospective multicenter study.

Blood

Avec: Stéphanie Guillet , Etienne Crickx , Imane Azzaoui , Pascal Chappert , Emmanuelle Boutin , Jean-François Viallard , Etienne Rivière , Delphine Gobert , Lionel Galicier , Marion Malphettes , Stéphane Cheze , François Lefrere , Sylvain Audia , Bernard Bonnotte , Olivier Lambotte , Nicolas Noel , Olivier Fain , Guillaume Moulis , Mohamed Hamidou , Mathieu Gerfaud-Valentin , Jean-Pierre Marolleau , Louis Terriou , Nihal Martis , Anne-Sophie Morin , Antoinette Perlat , Thomas Le Gallou , Frédérique Roy-Peaud , Ailsa Robbins , Jean-Christophe Lega , Matthieu Puyade , Thibault Comont , Nicolas Limal , Laetitia Languille , Anissa Zarrour , Marine Luka , Mickael Menager , Thibault Belmondo , Sophie Hue , Florence Canoui-Poitrine , Marc Michel , Bertrand Godeau , Matthieu Mahévas

Rituximab-resistant splenic memory B cells and newly engaged naive B cells fuel relapses in patients with immune thrombocytopenia.

Science translational medicine

Avec: Etienne Crickx , Pascal Chappert , Aurélien Sokal , Sandra Weller , Imane Azzaoui , Alexis Vandenberghe , Guillaume Bonnard , Geoffrey Rossi , Tatiana Fadeev , Sébastien Storck , Jehane Fadlallah , Véronique Meignin , Etienne Rivière , Sylvain Audia , Bertrand Godeau , Marc Michel , Jean-Claude Weill , Claude-Agnès Reynaud , Matthieu Mahévas

The whole-cell pertussis vaccine imposes a broad effector B cell response in mouse heterologous prime-boost settings.

JCI insight

Avec: Viviana Valeri , Akhésa Sochon , Clara Cousu , Pascal Chappert , Damiana Lecoeuche , Pascal Blanc , Jean-Claude Weill , Claude-Agnès Reynaud

Human anti-smallpox long-lived memory B cells are defined by dynamic interactions in the splenic niche and long-lasting germinal center imprinting.

Immunity

Avec: Pascal Chappert , François Huetz , Marie-Alix Espinasse , Fabrice Chatonnet , Louise Pannetier , Lucie Da Silva , Clara Goetz , Jérome Mégret , Aurélien Sokal , Etienne Crickx , Ivan Nemazanyy , Vincent Jung , Chiara Guerrera , Sébastien Storck , Matthieu Mahévas , Antonio Cosma , Patrick Revy , Thierry Fest , Claude-Agnès Reynaud , Jean-Claude Weill

Cross-Presentation of Skin-Targeted Recombinant Adeno-associated Virus 2/1 Transgene Induces Potent Resident Memory CD8

Journal of virology

Avec: David-Alexandre Gross , Alexandre Ghenassia , Laurent Bartolo , Dominique Urbain , Sofia Benkhelifa-Ziyyat , Stéphanie Lorain , Jean Davoust , Pascal Chappert

Immune Responses after a Third Dose of mRNA Vaccine Differ in Virus-Naive versus SARS-CoV-2- Recovered Dialysis Patients.

Clinical journal of the American Society of Nephrology : CJASN

Avec: Philippe Attias , Imane Azzaoui , Khalil El Karoui , Andréa de La Selle , Aurélien Sokal , Pascal Chappert , Philippe Grimbert , Ignacio Fernandez , Magali Bouvier , Chloé Samson , Djamal Dahmane , Philippe Rieu , Patrice Nizard , Slim Fourati , Hamza Sakhi , Matthieu Mahévas , Auteur inconnu

Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination.

The Journal of experimental medicine

Avec: Aurélien Sokal , Paul Bastard , Pascal Chappert , Giovanna Barba-Spaeth , Slim Fourati , Alexis Vanderberghe , Pauline Lagouge-Roussey , Isabelle Meyts , Adrian Gervais , Magali Bouvier-Alias , Imane Azzaoui , Ignacio Fernández , Andréa de la Selle , Qian Zhang , Lucy Bizien , Isabelle Pellier , Agnès Linglart , Anya Rothenbuhler , Estelle Marcoux , Raphael Anxionnat , Nathalie Cheikh , Juliane Léger , Blanca Amador-Borrero , Fanny Fouyssac , Vanessa Menut , Jean-Christophe Goffard , Caroline Storey , Caroline Demily , Coralie Mallebranche , Jesus Troya , Aurora Pujol , Marie Zins , Pierre Tiberghien , Paul E Gray , Peter McNaughton , Anna Sullivan , Jane Peake , Romain Levy , Laetitia Languille , Carlos Rodiguez-Gallego , Bertrand Boisson , Sébastien Gallien , Bénédicte Neven , Marc Michel , Bertrand Godeau , Laurent Abel , Felix A Rey , Jean-Claude Weill , Claude-Agnès Reynaud , Stuart G Tangye , Jean-Laurent Casanova , Matthieu Mahévas

Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models.

Science translational medicine

Avec: Alice Dejoux , Qianqian Zhu , Christelle Ganneau , Odile Richard-Le Goff , Ophélie Godon , Julien Lemaitre , Francis Relouzat , François Huetz , Aurélien Sokal , Alexis Vandenberghe , Cyprien Pecalvel , Lise Hunault , Thomas Derenne , Caitlin M Gillis , Bruno Iannascoli , Yidan Wang , Thierry Rose , Christel Mertens , Pascale Nicaise-Roland , Auteur inconnu , Patrick England , Matthieu Mahévas , Luc de Chaisemartin , Roger Le Grand , Hélène Letscher , Frederick Saul , Cédric Pissis , Ahmed Haouz , Laurent L Reber , Pascal Chappert , Friederike Jönsson , Didier G Ebo , Gaël A Millot , Sylvie Bay , Sylvie Chollet-Martin , Aurélie Gouel-Chéron , Pierre Bruhns

Induction of tumor-specific CTL responses using the C-terminal fragment of Viral protein R as cell penetrating peptide.

Scientific reports

Avec: D A Gross , C Leborgne , P Chappert , C Masurier , M Leboeuf , V Monteilhet , S Boutin , F A Lemonnier , J Davoust , A Kichler

Maturation and persistence of the anti-SARS-CoV-2 memory B cell response.

Cell

Avec: Aurélien Sokal , Pascal Chappert , Giovanna Barba-Spaeth , Anais Roeser , Slim Fourati , Imane Azzaoui , Alexis Vandenberghe , Ignacio Fernandez , Annalisa Meola , Magali Bouvier-Alias , Etienne Crickx , Asma Beldi-Ferchiou , Sophie Hue , Laetitia Languille , Marc Michel , Samia Baloul , France Noizat-Pirenne , Marine Luka , Jérôme Mégret , Mickaël Ménager , Jean-Michel Pawlotsky , Simon Fillatreau , Felix A Rey , Jean-Claude Weill , Claude-Agnès Reynaud , Matthieu Mahévas

Preschool-age children maintain a distinct memory CD4

Science translational medicine

Avec: Benoît Manfroi , Bui Thi Cuc , Aurélien Sokal , Alexis Vandenberghe , Sarah Temmam , Mikaël Attia , Mohamed El Behi , Francesco Camaglia , Ngan Thu Nguyen , Jelka Pohar , Layale Salem-Wehbe , Valentine Pottez-Jouatte , Sibyline Borzakian , Narcisse Elenga , Caroline Galeotti , Guillaume Morelle , Camille de Truchis de Lays , Michaela Semeraro , Anne-Sophie Romain , Mélodie Aubart , Naim Ouldali , Florence Mahuteau-Betzer , Claire Beauvineau , Elsa Amouyal , Romain Berthaud , Célia Crétolle , Marc Duval Arnould , Albert Faye , Mathie Lorrot , Grégoire Benoist , Nelly Briand , Marie Courbebaisse , Roland Martin , Peter Van Endert , Jean-Sébastien Hulot , Anne Blanchard , Eric Tartour , Maria Leite-de-Moraes , Guillaume Lezmi , Mickael Ménager , Marine Luka , Claude-Agnès Reynaud , Jean-Claude Weill , Laetitia Languille , Marc Michel , Pascal Chappert , Thierry Mora , Aleksandra M Walczak , Marc Eloit , Petra Bacher , Alexander Scheffold , Matthieu Mahévas , Isabelle Sermet-Gaudelus , Simon Fillatreau

Dual muscle-liver transduction imposes immune tolerance for muscle transgene engraftment despite preexisting immunity.

JCI insight

Avec: Laurent Bartolo , Stéphanie Li Chung Tong , Pascal Chappert , Dominique Urbain , Fanny Collaud , Pasqualina Colella , Isabelle Richard , Giuseppe Ronzitti , Jocelyne Demengeot , David A Gross , Federico Mingozzi , Jean Davoust

Foxp3

Frontiers in immunology

Avec: Mélanie Lalfer , Pascal Chappert , Maxime Carpentier , Dominique Urbain , Jean M Davoust , David-Alexandre Gross

BLI-MS: Combining biolayer interferometry and mass spectrometry.

Proteomics

Avec: Vincent Jung , Kévin Roger , Cerina Chhuon , Louise Pannetier , Joanna Lipecka , Josué Sulub Gomez , Pascal Chappert , Alain Charbit , Ida Chiara Guerrera

mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants.

Immunity

Avec: Aurélien Sokal , Giovanna Barba-Spaeth , Ignacio Fernández , Matteo Broketa , Imane Azzaoui , Andréa de La Selle , Alexis Vandenberghe , Slim Fourati , Anais Roeser , Annalisa Meola , Magali Bouvier-Alias , Etienne Crickx , Laetitia Languille , Marc Michel , Bertrand Godeau , Sébastien Gallien , Giovanna Melica , Yann Nguyen , Virginie Zarrouk , Florence Canoui-Poitrine , France Pirenne , Jérôme Mégret , Jean-Michel Pawlotsky , Simon Fillatreau , Pierre Bruhns , Felix A Rey , Jean-Claude Weill , Claude-Agnès Reynaud , Pascal Chappert , Matthieu Mahévas

Analysis of mRNA vaccination-elicited RBD-specific memory B cells reveals strong but incomplete immune escape of the SARS-CoV-2 Omicron variant.

Immunity

Avec: Aurélien Sokal , Matteo Broketa , Giovanna Barba-Spaeth , Annalisa Meola , Ignacio Fernández , Slim Fourati , Imane Azzaoui , Andrea de La Selle , Alexis Vandenberghe , Anais Roeser , Magali Bouvier-Alias , Etienne Crickx , Laetitia Languille , Marc Michel , Bertrand Godeau , Sébastien Gallien , Giovanna Melica , Yann Nguyen , Virginie Zarrouk , Florence Canoui-Poitrine , France Noizat-Pirenne , Jérôme Megret , Jean-Michel Pawlotsky , Simon Fillatreau , Etienne Simon-Lorière , Jean-Claude Weill , Claude-Agnès Reynaud , Félix A Rey , Pierre Bruhns , Pascal Chappert , Matthieu Mahévas

SARS-CoV-2 Omicron BA.1 breakthrough infection drives late remodeling of the memory B cell repertoire in vaccinated individuals.

Immunity

Avec: Aurélien Sokal , Giovanna Barba-Spaeth , Lise Hunault , Ignacio Fernández , Matteo Broketa , Annalisa Meola , Slim Fourati , Imane Azzaoui , Alexis Vandenberghe , Pauline Lagouge-Roussey , Manon Broutin , Anais Roeser , Magali Bouvier-Alias , Etienne Crickx , Laetitia Languille , Morgane Fournier , Marc Michel , Bertrand Godeau , Sébastien Gallien , Giovanna Melica , Yann Nguyen , Florence Canoui-Poitrine , France Pirenne , Jérôme Megret , Jean-Michel Pawlotsky , Simon Fillatreau , Claude-Agnès Reynaud , Jean-Claude Weill , Félix A Rey , Pierre Bruhns , Matthieu Mahévas , Pascal Chappert

Réseau de co-auteurs

Matthieu Mahévas 11 collaborations

Aurélien Sokal 10 collaborations

Jean-Claude Weill 9 collaborations

Claude-Agnès Reynaud 9 collaborations

Imane Azzaoui 8 collaborations

Marc Michel 8 collaborations

Etienne Crickx 7 collaborations

Laetitia Languille 7 collaborations

Alexis Vandenberghe 7 collaborations

Bertrand Godeau 6 collaborations

Slim Fourati 6 collaborations

Giovanna Barba-Spaeth 5 collaborations

Magali Bouvier-Alias 5 collaborations

Simon Fillatreau 5 collaborations

Florence Canoui-Poitrine 4 collaborations

Ignacio Fernández 4 collaborations

Sébastien Gallien 4 collaborations

Pierre Bruhns 4 collaborations

Anais Roeser 4 collaborations

Annalisa Meola 4 collaborations

Jean-Michel Pawlotsky 4 collaborations

Jean Davoust 3 collaborations

Marine Luka 3 collaborations

Dominique Urbain 3 collaborations

Felix A Rey 3 collaborations

Matteo Broketa 3 collaborations

Giovanna Melica 3 collaborations

Yann Nguyen 3 collaborations

David A Gross 2 collaborations

Etienne Rivière 2 collaborations

Sylvain Audia 2 collaborations

Sophie Hue 2 collaborations

Sébastien Storck 2 collaborations

François Huetz 2 collaborations

Louise Pannetier 2 collaborations

Vincent Jung 2 collaborations

David-Alexandre Gross 2 collaborations

Laurent Bartolo 2 collaborations

Andréa de La Selle 2 collaborations

Ignacio Fernandez 2 collaborations

None None 2 collaborations

Pauline Lagouge-Roussey 2 collaborations

Lise Hunault 2 collaborations

France Noizat-Pirenne 2 collaborations

Jérôme Mégret 2 collaborations

Virginie Zarrouk 2 collaborations

France Pirenne 2 collaborations

Jérôme Megret 2 collaborations

Félix A Rey 2 collaborations

Irini Evnouchidou 1 collaboration

Samira Benadda 1 collaboration

Andres Zucchetti 1 collaboration

Mirjana Weimershaus 1 collaboration

Marcelle Bens 1 collaboration

Vivien Caillens 1 collaboration

Despoina Koumantou 1 collaboration

Sophie Lotersztajn 1 collaboration

Peter van Endert 1 collaboration

Pierre Guermonprez 1 collaboration

Claire Hivroz 1 collaboration

Loredana Saveanu 1 collaboration

Stéphanie Guillet 1 collaboration

Emmanuelle Boutin 1 collaboration

Jean-François Viallard 1 collaboration

Delphine Gobert 1 collaboration

Lionel Galicier 1 collaboration

Marion Malphettes 1 collaboration

Stéphane Cheze 1 collaboration

François Lefrere 1 collaboration

Bernard Bonnotte 1 collaboration

Olivier Lambotte 1 collaboration

Nicolas Noel 1 collaboration

Olivier Fain 1 collaboration

Guillaume Moulis 1 collaboration

Mohamed Hamidou 1 collaboration

Mathieu Gerfaud-Valentin 1 collaboration

Jean-Pierre Marolleau 1 collaboration

Louis Terriou 1 collaboration

Nihal Martis 1 collaboration

Anne-Sophie Morin 1 collaboration

Antoinette Perlat 1 collaboration

Thomas Le Gallou 1 collaboration

Frédérique Roy-Peaud 1 collaboration

Ailsa Robbins 1 collaboration

Jean-Christophe Lega 1 collaboration

Matthieu Puyade 1 collaboration

Thibault Comont 1 collaboration

Nicolas Limal 1 collaboration

Anissa Zarrour 1 collaboration

Mickael Menager 1 collaboration

Thibault Belmondo 1 collaboration

Sandra Weller 1 collaboration

Guillaume Bonnard 1 collaboration

Geoffrey Rossi 1 collaboration

Tatiana Fadeev 1 collaboration

Jehane Fadlallah 1 collaboration

Véronique Meignin 1 collaboration

Viviana Valeri 1 collaboration

Akhésa Sochon 1 collaboration

Clara Cousu 1 collaboration

Damiana Lecoeuche 1 collaboration

Pascal Blanc 1 collaboration

Marie-Alix Espinasse 1 collaboration

Fabrice Chatonnet 1 collaboration

Lucie Da Silva 1 collaboration

Clara Goetz 1 collaboration

Jérome Mégret 1 collaboration

Ivan Nemazanyy 1 collaboration

Chiara Guerrera 1 collaboration

Antonio Cosma 1 collaboration

Patrick Revy 1 collaboration

Thierry Fest 1 collaboration

Alexandre Ghenassia 1 collaboration

Sofia Benkhelifa-Ziyyat 1 collaboration

Stéphanie Lorain 1 collaboration

Philippe Attias 1 collaboration

Khalil El Karoui 1 collaboration

Philippe Grimbert 1 collaboration

Magali Bouvier 1 collaboration

Chloé Samson 1 collaboration

Djamal Dahmane 1 collaboration

Philippe Rieu 1 collaboration

Patrice Nizard 1 collaboration

Hamza Sakhi 1 collaboration

Paul Bastard 1 collaboration

Alexis Vanderberghe 1 collaboration

Isabelle Meyts 1 collaboration

Adrian Gervais 1 collaboration

Andréa de la Selle 1 collaboration

Qian Zhang 1 collaboration

Lucy Bizien 1 collaboration

Isabelle Pellier 1 collaboration

Agnès Linglart 1 collaboration

Anya Rothenbuhler 1 collaboration

Estelle Marcoux 1 collaboration

Raphael Anxionnat 1 collaboration

Nathalie Cheikh 1 collaboration

Juliane Léger 1 collaboration

Blanca Amador-Borrero 1 collaboration

Fanny Fouyssac 1 collaboration

Vanessa Menut 1 collaboration

Jean-Christophe Goffard 1 collaboration

Caroline Storey 1 collaboration

Caroline Demily 1 collaboration

Coralie Mallebranche 1 collaboration

Jesus Troya 1 collaboration

Aurora Pujol 1 collaboration

Marie Zins 1 collaboration

Pierre Tiberghien 1 collaboration

Paul E Gray 1 collaboration

Peter McNaughton 1 collaboration

Anna Sullivan 1 collaboration

Jane Peake 1 collaboration

Romain Levy 1 collaboration

Carlos Rodiguez-Gallego 1 collaboration

Bertrand Boisson 1 collaboration

Bénédicte Neven 1 collaboration

Laurent Abel 1 collaboration

Stuart G Tangye 1 collaboration

Jean-Laurent Casanova 1 collaboration

Alice Dejoux 1 collaboration

Qianqian Zhu 1 collaboration

Christelle Ganneau 1 collaboration

Odile Richard-Le Goff 1 collaboration

Ophélie Godon 1 collaboration

Julien Lemaitre 1 collaboration

Francis Relouzat 1 collaboration

Cyprien Pecalvel 1 collaboration

Thomas Derenne 1 collaboration

Caitlin M Gillis 1 collaboration

Bruno Iannascoli 1 collaboration

Yidan Wang 1 collaboration

Thierry Rose 1 collaboration

Christel Mertens 1 collaboration

Pascale Nicaise-Roland 1 collaboration

Patrick England 1 collaboration

Luc de Chaisemartin 1 collaboration

Roger Le Grand 1 collaboration

Hélène Letscher 1 collaboration

Frederick Saul 1 collaboration

Cédric Pissis 1 collaboration

Ahmed Haouz 1 collaboration

Laurent L Reber 1 collaboration

Friederike Jönsson 1 collaboration

Didier G Ebo 1 collaboration

Gaël A Millot 1 collaboration

Sylvie Bay 1 collaboration

Sylvie Chollet-Martin 1 collaboration

Aurélie Gouel-Chéron 1 collaboration

D A Gross 1 collaboration

C Leborgne 1 collaboration

P Chappert 1 collaboration

C Masurier 1 collaboration

M Leboeuf 1 collaboration

V Monteilhet 1 collaboration

S Boutin 1 collaboration

F A Lemonnier 1 collaboration

J Davoust 1 collaboration

A Kichler 1 collaboration

Asma Beldi-Ferchiou 1 collaboration

Samia Baloul 1 collaboration

Mickaël Ménager 1 collaboration

Benoît Manfroi 1 collaboration

Bui Thi Cuc 1 collaboration

Sarah Temmam 1 collaboration

Mikaël Attia 1 collaboration

Mohamed El Behi 1 collaboration

Francesco Camaglia 1 collaboration

Ngan Thu Nguyen 1 collaboration

Jelka Pohar 1 collaboration

Layale Salem-Wehbe 1 collaboration

Valentine Pottez-Jouatte 1 collaboration

Sibyline Borzakian 1 collaboration

Narcisse Elenga 1 collaboration

Caroline Galeotti 1 collaboration

Guillaume Morelle 1 collaboration

Camille de Truchis de Lays 1 collaboration

Michaela Semeraro 1 collaboration

Anne-Sophie Romain 1 collaboration

Mélodie Aubart 1 collaboration

Naim Ouldali 1 collaboration

Florence Mahuteau-Betzer 1 collaboration

Claire Beauvineau 1 collaboration

Elsa Amouyal 1 collaboration

Romain Berthaud 1 collaboration

Célia Crétolle 1 collaboration

Marc Duval Arnould 1 collaboration

Albert Faye 1 collaboration

Mathie Lorrot 1 collaboration

Grégoire Benoist 1 collaboration

Nelly Briand 1 collaboration

Marie Courbebaisse 1 collaboration

Roland Martin 1 collaboration

Peter Van Endert 1 collaboration

Jean-Sébastien Hulot 1 collaboration

Anne Blanchard 1 collaboration

Eric Tartour 1 collaboration

Maria Leite-de-Moraes 1 collaboration

Guillaume Lezmi 1 collaboration

Mickael Ménager 1 collaboration

Thierry Mora 1 collaboration

Aleksandra M Walczak 1 collaboration

Marc Eloit 1 collaboration

Petra Bacher 1 collaboration

Alexander Scheffold 1 collaboration

Isabelle Sermet-Gaudelus 1 collaboration

Stéphanie Li Chung Tong 1 collaboration

Fanny Collaud 1 collaboration

Pasqualina Colella 1 collaboration

Isabelle Richard 1 collaboration

Giuseppe Ronzitti 1 collaboration

Jocelyne Demengeot 1 collaboration

Federico Mingozzi 1 collaboration

Mélanie Lalfer 1 collaboration

Maxime Carpentier 1 collaboration

Jean M Davoust 1 collaboration

Kévin Roger 1 collaboration

Cerina Chhuon 1 collaboration

Joanna Lipecka 1 collaboration

Josué Sulub Gomez 1 collaboration

Alain Charbit 1 collaboration

Ida Chiara Guerrera 1 collaboration

Andrea de La Selle 1 collaboration

Etienne Simon-Lorière 1 collaboration

Manon Broutin 1 collaboration

Morgane Fournier 1 collaboration